American Airlines flight AA 4650: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Mon-Fri 06:00 Madison (MSN) 09:13 Ronald Reagan Washington (DCA) 2
AA 4650 Non-stop Embraer EMB 175 (E75) 2:13 Effective 2025-06-06 through 2025-07-04
Mon-Fri 06:00 Madison (MSN) 09:14 Ronald Reagan Washington (DCA) 2
AA 4650 Non-stop Embraer EMB 175 (E75) 2:14 Effective 2025-07-07 through 2025-08-05
Thu 06:03 Memphis (MEM) 09:19 Ronald Reagan Washington (DCA) 2
AA 4650 Non-stop Embraer EMB 175 (E75) 2:16 Operates only on 2025-06-05
Sun 08:19 Ronald Reagan Washington (DCA) 2 09:54 Pensacola (PNS)
AA 4650 Non-stop Embraer EMB 175 (E75) 2:35 Effective 2025-06-08 through 2025-06-29
Sun 10:24 Pensacola (PNS) 13:52 Ronald Reagan Washington (DCA) 2
AA 4650 Non-stop Embraer EMB 175 (E75) 2:28 Effective 2025-06-08 through 2025-06-29
Daily 10:36 Raleigh/Durham (RDU) 2 11:18 Nashville (BNA)
AA 4650 Non-stop Embraer EMB 175 (E75) 1:42 Effective 2025-09-03 through 2025-10-05
Mon-Fri 11:12 New York LaGuardia (LGA) B 12:24 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 1:12 Effective 2025-05-05 through 2025-06-04
Mon-Fri,Sun 11:15 New York LaGuardia (LGA) B 12:28 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 1:13 Valid until 2025-05-04
Mon-Fri,Sun 13:00 Boston Logan (BOS) B 14:20 New York LaGuardia (LGA) B
AA 4650 Non-stop Embraer EMB 175 (E75) 1:20 Effective 2025-05-05 through 2025-06-04
Daily 13:43 Boston Logan (BOS) B 15:00 New York LaGuardia (LGA) B
AA 4650 Non-stop Embraer EMB 175 (E75) 1:17 Valid until 2025-05-04
Sat 20:20 Chicago O'Hare (ORD) 3 00:09 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:49 Effective 2025-07-05 through 2025-08-02
The flight arrives 1 day after departure.
Daily 20:20 Chicago O'Hare (ORD) 3 23:52 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:32 Effective 2025-11-02 through 2025-12-02
Daily 20:20 Chicago O'Hare (ORD) 3 00:05 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:45 Effective 2025-12-18 through 2026-01-05
The flight arrives 1 day after departure.
Daily 20:20 Chicago O'Hare (ORD) 3 23:45 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:25 Effective 2026-01-06 through 2026-02-11
Daily 20:20 Chicago O'Hare (ORD) 3 23:38 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:18 Effective from 2026-02-12
Daily 20:35 Chicago O'Hare (ORD) 3 00:10 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:35 Effective 2025-12-03 through 2025-12-17
The flight arrives 1 day after departure.
Sat 20:40 Chicago O'Hare (ORD) 3 00:26 Boston Logan (BOS) B
AA 4650 Non-stop Embraer EMB 175 (E75) 2:46 Effective 2025-06-07 through 2025-06-28
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:


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American Airlines flight AA 4650: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA4650
06:00
Madison (MSN)

09:13
Ronald Reagan Washington (DCA) 2
Effective 2025-06-06 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
06:00
Madison (MSN)

09:14
Ronald Reagan Washington (DCA) 2
Effective 2025-07-07 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 2:14, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
06:03
Memphis (MEM)

09:19
Ronald Reagan Washington (DCA) 2
Operates only on 2025-06-05
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 2:16, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
08:19
Ronald Reagan Washington (DCA) 2

09:54
Pensacola (PNS)
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:35, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
10:24
Pensacola (PNS)

13:52
Ronald Reagan Washington (DCA) 2
Effective 2025-06-08 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:28, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
10:36
Raleigh/Durham (RDU) 2

11:18
Nashville (BNA)
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:42, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
11:12
New York LaGuardia (LGA) B

12:24
Boston Logan (BOS) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
-
Duration: 1:12, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
11:15
New York LaGuardia (LGA) B

12:28
Boston Logan (BOS) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:13, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
13:00
Boston Logan (BOS) B

14:20
New York LaGuardia (LGA) B
Effective 2025-05-05 through 2025-06-04
Mon
Tue
Wed
Thu
Fri
Sat
-
Sun
Duration: 1:20, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
13:43
Boston Logan (BOS) B

15:00
New York LaGuardia (LGA) B
Valid until 2025-05-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:17, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
20:20
Chicago O'Hare (ORD) 3

00:09(+1)
Boston Logan (BOS) B
Effective 2025-07-05 through 2025-08-02
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:49, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
American Airlines AA4650
20:20
Chicago O'Hare (ORD) 3

23:52
Boston Logan (BOS) B
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:32, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
20:20
Chicago O'Hare (ORD) 3

00:05(+1)
Boston Logan (BOS) B
Effective 2025-12-18 through 2026-01-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:45, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
American Airlines AA4650
20:20
Chicago O'Hare (ORD) 3

23:45
Boston Logan (BOS) B
Effective 2026-01-06 through 2026-02-11
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:25, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
20:20
Chicago O'Hare (ORD) 3

23:38
Boston Logan (BOS) B
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:18, non-stop
Embraer EMB 175 (E75)
American Airlines AA4650
20:35
Chicago O'Hare (ORD) 3

00:10(+1)
Boston Logan (BOS) B
Effective 2025-12-03 through 2025-12-17
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:35, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
American Airlines AA4650
20:40
Chicago O'Hare (ORD) 3

00:26(+1)
Boston Logan (BOS) B
Effective 2025-06-07 through 2025-06-28
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:46, non-stop
Embraer EMB 175 (E75)
The flight arrives 1 day after departure.
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This flight number is listed as serving the following routes:
  • Boston Logan (BOS) - New York LaGuardia (LGA)
  • Chicago O'Hare (ORD) - Boston Logan (BOS)
  • Madison (MSN) - Ronald Reagan Washington (DCA)
  • Memphis (MEM) - Ronald Reagan Washington (DCA)
  • Raleigh/Durham (RDU) - Nashville (BNA)
  • Ronald Reagan Washington (DCA) - Pensacola (PNS)
All American Airlines flights
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